CellMix : Sample Analyses

Gene expression experiments are commonly performed using samples that are composed of a variety of cell types, each contributing to the global gene expression measurements in different proportions. The CellMix package defines a general framework for gene expression deconvolution that integrates several of the currently available deconvolution algorithms, and facilitates the estimation of cell type proportions and/or cell-specific differential expression in gene expression experiments. The package was designed to handle common data settings using a unified interface, and to help in dealing with specific issues such as cross-platform/species identifier conversions. This vignette illustrates some of the package’s key functionalities on practical sample analyses.